Alfa’s partner, Gattefossé, provides innovative, safe and cost effective excipients for the development creams, lotions, gels and microemulsions.
These excipients help combine pharmaceutical quality, therapeutic efficacy and consumer acceptability into distinct topical formulations designed to:
Improve drug delivery
Emulsify poorly soluble drugs
Improve product stability
Improve product aesthetics and feel
Improve process parameters
Reduce manufacturing costs
Emulsifiers
Emulsifying bases are designed to allow the simple formulation of safe, effective and stable topical formulations from sprayable fluid emulsions to thick creams. Once selected, the process is simple - heat and mix with water.
For expert advice from our technical department on solving your formulation problems, or to request further information or samples of any of our excipients, please contact us or submit your query via the info request form.
Mark tick box to add excipient to info request form
Non-ionic o/w emulsifiers
Product
Chemical Description
HLB Value
Aplications
Melting Point
(Drop Piont)
Apifil®
PEG-8 beeswax
9
For emulsions containing high levels of oily phase. From 5 to 15%, it forms stable creams with firm texture and glossy appearance. For light creams, use levels of under 5% in association with an aqueous gelifying agent are recommended.
59.0
Gelot 64
Glyceryl stearate (and) PEG-75 stearate
10
For emulsions containing difficult-to-formulate active drugs, alcohol extracts or essential oils. From 7 to 20%, it forms creams with firm texture, has excellent heat stability and is compatible in systems covering wide pH ranges.
67.5
Plurol® stearique WL 1009
Polyglyceryl-6 distearate
9
A PEG-free emulsifier for sensitive skin. It is well-suited for the emulsification of vegetable oils at levels above 5% in association with an aqueous gelifying agent.
For multipurpose types of O/W emulsions. From 8 to 20%, it forms elegant and stable creams with firm texture and excellent mucosal tolerance. Widely used in vaginal applications. For light creams, use levels of under 8% in association with an aqueous gelifying agent are recommended.
48.0
Tefose® 1500
PEG-6 stearate (and) PEG-32 stearate
10
For lotions or emulsifier with light texture. It is polyvalent and compatible with all types of oils. From 8 to 12%, it forms light and soft creams. Below 8%, it forms fluid to very fluid lotions.
43.0
Non-ionic w/o emulsifiers
Product
Chemical Description
HLB Value
Aplications
Melting Point
(Drop Piont)
Plurol® Diisostearique
Polyglyceryl-3 Diisostearate
4.5
A PEG-free multipurpose W/O emulsifier. From 3 to 6%, it forms elegant and stable creams with firm texture. Strongly recommended for thermosensitive drugs requiring cold processing.
For emulsions containing difficult-to-formulate active drugs, alcoholic extracts or essential oils. From 8 to 20%, it forms creams with firm texture and has excellent heat stability. Suitable for development of anhydrous creams containing PEGs or Glycerine.
